Cognitive Deficits in Brain Disorders

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This understanding could lead to novel insights for future intervention strategies, from early detection to prevention of cognitive dysfunctions. The collegial atmosphere of this meeting, with programmed discussion sessions and opportunities for informal gatherings in the afternoons and evenings, provides an avenue for scientists from different disciplines to brainstorm and promotes cross-disciplinary collaborations in the various research areas represented. FAQs Instant answers to common questions. These callers are not authorized by GRC or the hotel.

Details are available by clicking here. May 12 - 17, Vice Chairs Sandra S. Chan and Nicola Lautenschlager.


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Contact Chairs. Conference Description. Conference Program. Sunday pm - pm Arrival and Check-in. Genetic Influences on Cognitive Development This session will highlight the impact of genetic variation on cognitive and brain development as evidenced from work in non-human primates and human genetic epidemiology. Neurodegeneration: Genetic, Pathophysiology and Biomarkers of Alzheimer's Disease This session will highlight the search for the pathophysiology mechanism, biomarkers, neuroimaging and genetics of Alzheimer's disease.

The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring. Genes, Cognitive Dysfunction and Mental Disorders This session will highlight the intertwining relationship between genetics, cognitive dysfunction and major mental disorders.

Cognitive Impairment in Multiple Sclerosis | Dana Foundation

Transdiagnostic Boundary Across Mental Disorders This session will highlight the highlight the transdiagnostic boundary, overlap and differences across mental disorders. Discussion Leader: Eric Y. Adolescence as a Critical Period of Vulnerability for Neuropsychiatric Problems This session will highlight the critical period of adolescence in the remodeling of neuronal circuitry, predisposition to neuropsychiatric problems as evidenced from epidemiology, imaging and population cohorts.

Conference Description.

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Almost all brain disorders are associated with cognitive impairment. For many clinicians and neuroscientists, cognitive dysfunction is specific for dementia.

It is not until recently that the research community has come to appreciate that the degree of cognitive impairment in different brain diseases defines functional outcomes. Understanding the mechanisms underlying cognitive dysfunction in various brain diseases, their similarities and differences, will informs new strategies for prevention and treatment. In the past years, much progress has been obtained in the possibilities to assess the neurobiology of cognition with sophisticated assessment and advanced brain imaging techniques, which have greatly enhanced our understanding of the basis of cognitive deficits.

More importantly, advanced imaging and genetic evaluations have started to elucidate the impact of lifestyle factors such as physical exercise, nutrition, sleep and biorhythm on cognitive functioning. Consolidation of knowledge in these areas is the key for the development of new treatment regimens, as across disorders there is little evidence for effective treatments to improve cognition at present. The specific aims of this GRC are to bring together experts to share their recent research on the assessment of cognitive dysfunction in different brain disorders using advanced imaging, genetic and cognitive assessment techniques, and on the exploration of innovative lifestyle modulators of brain reserve, neuroplasticity and cognition.

The experience of evaluating and intervening cognitive dysfunction through multimodal assessment schema across different brain disorders will hopefully converge to define a new paradigm for transdiagnostic approach towards intervention for optimization of cognition.

At the Heart of Brain Disorders – Preventing Cognitive Decline and Dementia

Conference Program. Sunday pm - pm Arrival and Check-in. Beyond the Boundaries of Diagnoses Across the Lifespan This session will highlight the dimension of cognitive dysfunction across major brain diseases in different age groups, drawing the similarity beyond current framework for diagnostic classifications. Genetics and Behavior Advanced genetic evaluation has provided important insights into the development of major neuropsychiatric conditions. Recent explorations appear to inform the clustering of constitutional predisposed physiological functions that modulate behaviors independent of diagnosis.

This session will draw the links between genetic studies, cognitive and behavioral disorders. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.

Imaging Cognitive Function and Dysfunction in Alzheimer's Disease and Other Neurocognitive Disorders The state of the art neuroimaging techniques in elucidating underlying mechanisms for cognitive dysfunction will be introduced. Presentations will expand from the framework of degenerative conditions to other brain disorders. Physical Activity, Nutrition and the Ageing Brain There has been increasing interests in the relationship between physical activity, diet and brain function.

The protective effects of these lifestyle activities in cognition have mostly been evaluated in older adults. However, the putative mechanisms are not only specific for the ageing brain. This session will discuss on the potential for further research beyond the current paradigm.

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